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The spectrum of laser skin resurfacing: nonablative, fractional, and ablative laser resurfacing

This review describes ablative, fractional and nonablative laser resurfacing and states that ablative lasers give the largest improvement, while the other two are more popular because they carry less risk and a shorter recovery.

Alexiades-Armenakas MR, Dover JS, Arndt KA. Journal of the American Academy of Dermatology, 2008.

What it means for a patient

  • Ablative laser removes the outer skin and gives the largest change, with about 2 weeks of recovery and a small risk of complications.
  • Nonablative laser heats the deeper skin and leaves the surface in place.
  • Fractional laser treats tiny columns of skin and sits between the other two in both results and recovery time.
  • The choice among them weighs the size of the result against recovery time and risk.
  • This is a review. It reports no new patient results.

Why this paper matters

It set out the range of laser resurfacing types, nonablative, fractional and ablative, with the trade-off between result, recovery and risk for each.

Overview

Laser resurfacing began in the 1980s with continuous-wave carbon dioxide (CO2) lasers, which had a high rate of side effects, including scarring. Pulsed CO2 and erbium lasers followed and removed skin in a controlled way. Their 2-week recovery and small but real complication risk led to nonablative and then fractional lasers. The article is a continuing medical education review.

Findings

  • Continuous-wave CO2 lasers (1980s) had a high rate of side effects, including scarring.
  • Short-pulse, high-peak-power, rapidly scanned CO2 lasers and normal-mode erbium:YAG lasers were developed to remove skin in a precisely controlled way.
  • Ablative resurfacing: about a 2-week recovery and a small but significant complication risk.
  • Nonablative resurfacing heats the dermis to improve wrinkles and sun damage while keeping the outer skin layer intact.
  • Fractional resurfacing ablates microscopic columns of skin in a regular pattern over a fraction of the skin surface.
  • Fractional lasers are more effective than nonablative lasers and give faster recovery than ablative lasers.
  • Neither nonablative nor fractional resurfacing gives results comparable to ablative resurfacing.
  • Both have become much more popular than ablative resurfacing, because the risks are limited and the improvement acceptable.
  • The abstract gives no patient data.

Terms

  • Laser resurfacing: using a laser to remove or heat layers of skin so new skin forms.
  • Ablative: removes the outer layers of skin.
  • Nonablative: heats the deeper skin without removing the surface.
  • Fractional: treats many tiny columns of skin and leaves the skin between them untouched.
  • CO2 laser: a laser that uses carbon dioxide gas, used for ablative resurfacing.
  • Erbium:YAG laser: a laser that removes thin layers of skin with less heat spread.
  • Epidermis: the outer layer of the skin.
  • Dermis: the deeper layer of the skin that holds collagen.
  • Rhytides: wrinkles.
  • Photodamage: skin damage from sun exposure.

Newest papers on co2 laser resurfacing

The latest studies on the same subject.

2026
A comparative study of efficacy of fractional carbon dioxide laser with and without subcision in treatment of facial acne scars
Johnson RA, Swaroop MR, Yogesh D, Panigrahi S, Namratha G, Greeshma J, et al. · J Cosmet Laser Ther · PMID 42178734
2026
Full-face carbon dioxide laser resurfacing: a patient's perspective
Affleck A, Lee ML, Convery C, Demirel S · Clin Exp Dermatol · PMID 41369004

More plain summaries on co2 laser resurfacing

2026
Topical Carboxytherapy as an Adjunct to Skin Recovery Post-CO2 Laser Fractional Resurfacing
Hernandez-Rovira B, Villamaria E, Purushothaman KR, Ziebart R, Ozarslan B, Shamban A, et al. · J Drugs Dermatol · Randomized Controlled Trial · PMID 42696341 · Plain summary